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Genome-Wide Methylation Analyses in Glioblastoma Multiforme

21 Feb 2014

Abstract excerpt

Few studies had investigated genome-wide methylation in glioblastoma multiforme (GBM). Our goals were to study differential methylation across the genome in gene promoters using an array-based method, as well as repetitive elements using surrogate global methylation markers. The discovery sample set for this study consisted of 54 GBM from Columbia University and Case Western Reserve University, and 24 brain...

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PMID: 24586730
DOI: 10.1371/journal.pone.0089376

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