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Article

A novel Bayesian method for detection of APOBEC3-mediated hypermutation and its application to zoonotic transmission of simian foamy viruses.

PLoS computational biology - 1 Feb 2014

Matsen Frederick A, Small Christopher T, Soliven Khanh, Engel Gregory A, Feeroz Mostafa M, Wang Xiaoxing, Craig Karen L, Hasan M Kamrul, Emerman Michael, Linial Maxine L, Jones-Engel Lisa

Abstract excerpt

Simian Foamy Virus (SFV) can be transmitted from non-human primates (NHP) to humans. However, there are no documented cases of human to human transmission, and significant differences exist between infection in NHP and human hosts. The mechanism for these between-host differences is not completely understood. In this paper we develop a new Bayesian approach to the detection of APOBEC3-mediated hypermutation, and...

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Identifiers

PMID: 24586139
DOI: 10.1371/journal.pcbi.1003493
PMCID: PMC3937129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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