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Host Switch Leads to Emergence of Plasmodium vivax Malaria in Humans

27 Apr 2005

Abstract excerpt

The geographical origin of Plasmodium vivax, the most widespread human malaria parasite, is controversial. Although genetic closeness to Asian primate malarias has been confirmed by phylogenetic analyses, genetic similarities between P. vivax and Plasmodium simium, a New World primate malaria, suggest that humans may have acquired P. vivax from New World monkeys or vice versa. Additionally, the near fixation of...

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PMID: 15858201
DOI: 10.1093/molbev/msi160

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