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The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching

30 Sept 2021

Abstract excerpt

BACKGROUND: Plasmodium simium, a malaria parasite of non-human primates (NHP), was recently shown to cause zoonotic infections in humans in Brazil. We sequenced the P. simium genome to investigate its evolutionary history and to identify any genetic adaptions that may underlie the ability of this parasite to switch between host species. RESULTS: Phylogenetic analyses based on whole genome sequences of P. simium...

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PMID: 34592986
DOI: 10.1186/s12915-021-01139-5

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