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Article

A novel mutation in the thyroglobulin gene that causes goiter and dwarfism in Wistar Hannover GALAS rats.

Mutation research - 1 Apr 2014

Sato Akira, Abe Kuniya, Yuzuriha Misako, Fujii Sakiko, Takahashi Naofumi, Hojo Hitoshi, Teramoto Shoji, Aoyama Hiroaki

Abstract excerpt

Outbred stocks of rats have been used extensively in biomedical, pharmaceutical and/or toxicological studies as a model of genetically heterogeneous human populations. One of such stocks is the Wistar Hannover GALAS rat. However, the colony of Wistar Hannover GALAS rat has been suspected of keeping a problematic mutation that manifests two distinct spontaneous abnormalities, goiter and dwarfism, which often...

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Source

Identifiers

PMID: 24582622
DOI: 10.1016/j.mrfmmm.2014.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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