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Article

Molecular advances in thyroglobulin disorders.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2006

Rivolta Carina M, Targovnik Héctor M

Abstract excerpt

Synthesis of tri-iodothyronine (T(3)) and thyroxine (T(4)) follows a metabolic pathway that depends on the integrity of the thyroglobulin structure. This large glycoprotein is a homodimer of 660 kDa synthesized and secreted by the thyroid cells into the lumen of thyroid follicle. In humans it is coded by a single copy gene, 270 kb long, that maps on chromosome 8q24 and contains an 8.5 kb coding sequence divided...

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Identifiers

PMID: 16870170
DOI: 10.1016/j.cca.2006.05.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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