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Article

MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes

28 Feb 2014

Abstract excerpt

Osteoarthritis is a common cause of functional deterioration in older adults and is an immense burden on the aging population. Altered chondrogenesis is the most important pathophysiological process involved in the development of osteoarthritis. However, the molecular mechanism underlying the regulation of chondrogenesis in patients with osteoarthritis requires further elucidation, particularly with respect to...

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PMID: 24577233
DOI: 10.1038/emm.2013.152

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