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Article

A Role for Bone Morphogenetic Protein-4 in Adipocyte Development

15 Feb 2007

Abstract excerpt

Obesity is characterized by increases in the number of mature adipocytes. Nascent adipocytes arise from mesenchymal stem cells (MSCs) by a multi-step process--MSCs are recruited to the adipocyte lineage forming determined preadipocytes, these committed progenitors proliferate, undergo growth arrest, and finally differentiate into mature adipocytes. Although the genetic mechanisms that control the differentiation...

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PMID: 17314508
DOI: 10.4161/cc.6.4.3804

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