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Article

Assessing tissue damage in multiple sclerosis: a biomarker approach

24 Feb 2014

Abstract excerpt

OBJECTIVES: Magnetic resonance imaging (MRI) of the brain and spinal cord is the gold standard for assessing disease activity in multiple sclerosis (MS). MRI is an excellent instrument for determination of accumulated damage to the brain and spinal cord, but tells us little about ongoing tissue damage. In this study, biomarkers of oligodendrocyte, axonal and astrocyte injury were related to MRI and clinical...

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PMID: 24571714
DOI: 10.1111/ane.12239

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