Article
The role of the nuclear lamina in cancer and apoptosis.
Advances in experimental medicine and biology - 1 Jan 2014
Broers Jos L V, Ramaekers Frans C S
Abstract excerpt
Not long after the discovery of lamin proteins, it became clear that not all lamin subtypes are ubiquitously expressed in cells and tissues. Especially, A-type lamins showed an inverse correlation with proliferation and were thus initially called statins. Here we compare the findings of both A- and B-type lamin expression in various normal tissues and their neoplastic counterparts. Based on immunocytochemistry it...
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