Article
Association of interleukin-1β -511 C/T polymorphism with tobacco-associated cancer in northeast India: a study on oral and gastric cancer.
Cancer genetics - 1 Jan 2000
Lakhanpal Meena, Yadav Dhirendra Singh, Devi Thoudam Regina, Singh Laishram Chandreshwor, Singh Khangembam Jitenkumar, Latha Santhi P, Chauhan Pradeep Singh, Verma Yogesh, Zomavia Eric, Sharma Jagannath, Chandra Kataki Amal, Saxena Sunita, Kapur Sujala
Abstract excerpt
The IL-1β -511 C/T polymorphism is associated with increased IL-1 production and with increased risk of developing cancers. In this study, 251 patients (125 with gastric cancer [GC] and 126 with oral cancer [OC]) and 207 normal controls from northeast (NE) India were genotyped for the IL-1β -511 C/T polymorphism by PCR-restriction fragment length polymorphism (RFLP) and sequencing. Analysis of results showed...
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