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Article

MYCN gene expression is required for the onset of the differentiation programme in neuroblastoma cells

20 Feb 2014

Abstract excerpt

Neuroblastoma is an embryonic tumour of the sympathetic nervous system and is one of the most common cancers in childhood. A high differentiation stage has been associated with a favourable outcome; however, the mechanisms governing neuroblastoma cell differentiation are not completely understood. The MYCN gene is considered the hallmark of neuroblastoma. Even though it has been reported that MYCN has a role...

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PMID: 24556696
DOI: 10.1038/cddis.2014.42

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