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UVB irradiation does not directly induce detectable changes of DNA methylation in human keratinocytes

13 Feb 2013

Abstract excerpt

Unprotected exposure to UVB radiation from the sun and the resulting DNA damage are thought to be responsible for physiological changes in the skin and for a variety of skin cancers, including basal cell and squamous cell carcinoma and malignant melanoma. Although the mutagenic effects of UVB have been well documented and studied mechanistically, there is only limited information as to whether UV light may also...

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PMID: 24555035
DOI: 10.12688/f1000research.2-45.v1

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