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Article

Trichomonas vaginalis metronidazole resistance is associated with single nucleotide polymorphisms in the nitroreductase genes ntr4Tv and ntr6Tv.

Antimicrobial agents and chemotherapy - 1 May 2014

Paulish-Miller Teresa E, Augostini Peter, Schuyler Jessica A, Smith William L, Mordechai Eli, Adelson Martin E, Gygax Scott E, Secor William E, Hilbert David W

Abstract excerpt

Metronidazole resistance in the sexually transmitted parasite Trichomonas vaginalis is a problematic public health issue. We have identified single nucleotide polymorphisms (SNPs) in two nitroreductase genes (ntr4Tv and ntr6Tv) associated with resistance. These SNPs were associated with one of two distinct T. vaginalis populations identified by multilocus sequence typing, yet one SNP (ntr6Tv A238T), which results...

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Identifiers

PMID: 24550324
DOI: 10.1128/AAC.02370-13
PMCID: PMC3993245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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