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Article

A pilot study of leukocyte expression patterns for drug metabolizing enzyme and transporter transcripts in autoimmune glomerulonephritis.

International journal of clinical pharmacology and therapeutics - 1 Apr 2014

Joy Melanie S, Roberts Brittney V, Wang Jinzhao, Hu Yichun, Hogan Susan L, Falk Ronald J

Abstract excerpt

OBJECTIVE: Leukocyte mRNA expression patterns of drug metabolizing enzyme genes and transporter genes that are relevant for the disposition of cyclophosphamide and mycophenolate were studied. The relationships between expression and patient-level data and pharmacokinetics were evaluated. METHODS: The study included patients with glomerulonephritis secondary to lupus nephritis (SLE, n = 36), small vessel...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24548980
DOI: 10.5414/CP201972
PMCID: PMC4123858

Genes

ABCC2
ABCB1
UGT1A7
ABCG2
CYP2B6
CYP2C9
CYP3A4
SLCO1A2
UGT1A9
UGT2B7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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