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Article

Overexpression of AGR2 Is Associated With Drug Resistance in Mutant Non-small Cell Lung Cancers.

Anticancer research - 1 Apr 2020

Luu Thi-Thu-Trang, Bach Duc-Hiep, Kim Donghwa, Hu Ruoci, Park Hyen Joo, Lee Sang Kook

Abstract excerpt

BACKGROUND/AIM: The resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib or erlotinib, is considered a major challenge in the treatment of patients with non-small cell lung cancer (NSCLC). Herein, we identified the critical roles of anterior gradient 2 (AGR2) in gefitinib (Gef) resistance of mutant NSCLC cells. MATERIALS AND METHODS: Using datasets from a pair...

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Identifiers

PMID: 32234873
DOI: 10.21873/anticanres.14139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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