Article
Germline genetic variants associated with prostate cancer and potential relevance to clinical practice.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer - 1 Jan 2014
Goh Chee Leng, Eeles Rosalind Anne
Abstract excerpt
The inherited link of prostate cancer predisposition has been supported using data from early epidemiological studies, as well as from familial and twin studies. Early linkage analyses and candidate gene approaches to identify these variants yielded mixed results. Since then, multiple genetic variants associated with prostate cancer susceptibility have now been found from genome-wide association studies (GWAS)....
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