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Article

IDH1 overexpression induced chemotherapy resistance and IDH1 mutation enhanced chemotherapy sensitivity in Glioma cells in vitro and in vivo.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Wang Ju-Bo, Dong Dan-Feng, Wang Mao-De, Gao Ke

Abstract excerpt

Isocitrate dehydrogenase (IDH) is of great importance in cell metabolism and energy conversion. IDH mutation in glioma cells is reported to be associated with an increased overall survival. However, effects biological behavior of therapy of gliomas are unclear. Here, we investigated the influence...

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Share to Antineoplastic Agents, Alkylating
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Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to G1 Phase Cell Cycle Checkpoints

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Share to Isocitrate Dehydrogenase

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Source

Identifiers

PMID: 24528069
DOI: 10.7314/apjcp.2014.15.1.427

Genes

IDH1
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24528069-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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IDH1 overexpression induced chemotherapy resistance and IDH1 mutation enhanced chemotherapy sensitivity in Glioma cells in vitro and in vivo.PMID 24528069Read ↗

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