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Article

Genomic profiling of early-stage resectable non-small-cell lung cancer in a Malaysian private healthcare setting: Real-world clinical implications.

The Medical journal of Malaysia - 1 Jan 2026

Sachithanandan A, Hoh H H, Lam M D, Low E C, Yap N Y, Hassanudin S A, Ten Y Y, Tan P K, Naim C K, Lutfi F N M, Yong W W S, Sachithananthan S, Yap X L, Rajadurai P

Abstract excerpt

INTRODUCTION: The prevalence of oncogenic driver mutations in early-stage resectable non-small-cell lung cancer (rNSCLC) in Malaysia remains unknown. This information may guide treatment decisions, especially tyrosine kinase inhibitor (TKI) use. We characterised the genomic landscape of early-stage NSCLC in a surgical cohort and explored its impact on TKI administration, particularly osimertinib. MATERIALS AND...

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Identifiers

PMID: 41617518

Genes

EGFR
CTNNB1
PTEN
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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