Molecular Mechanisms of Biofilm Infection: Biofilm Virulence Factors

Abstract excerpt

BACKGROUND: Numerous planktonic virulence factors have been identified that enable bacteria to successfully produce acute infections in tissues. In contrast, very little is known about biofilm virulence factors that enhance the establishment and long-term survival of biofilms in tissues. THE PROBLEM: There is a need to identify the genes that encode biofilm virulence factors and understand how these factors...

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