Article
New antiretroviral agent use affects prevalence of HIV drug resistance in clinical care populations.
AIDS (London, England) - 13 Nov 2018
Davy-Mendez Thibaut, Eron Joseph J, Brunet Laurence, Zakharova Oksana, Dennis Ann M, Napravnik Sonia
Abstract excerpt
OBJECTIVE: To estimate the prevalence of HIV drug resistance over time and identify risk factors for multiclass resistance. DESIGN: Prospective clinical cohort of HIV-infected patients at the University of North Carolina. METHODS: Among antiretroviral therapy (ART)-experienced patients in care 2000-2016, we estimated annual prevalences of cumulative resistance, defined as at least one major mutation by drug...
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