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Article

Association of TLR7 and TSHR copy number variation with Graves' disease and Graves' ophthalmopathy in Chinese population in Taiwan.

BMC ophthalmology - 11 Feb 2014

Liao Wen-Ling, Wan Lei, Wang Tzu-Yuan, Chen Ching-Chu, Tse Siu-San, Lu Chieh-Hsiang, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Graves' disease (GD) and Graves' ophthalmopathy (GO) are autoimmune disorders, which might be influenced by genetic factors. Copy number variation (CNV) is an important source of genomic diversity in humans, and influences disease susceptibility. This study investigated the association between CNV in the TSHR and TLR7 genes and the development of GD and GO in a Chinese population in Taiwan. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24517461
DOI: 10.1186/1471-2415-14-15
PMCID: PMC3929160

Genes

TLR7
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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