Article
Phosphoproteomic Analysis Reveals Regulatory Mechanisms at the Kidney Filtration Barrier
8 Feb 2014
Abstract excerpt
Diseases of the kidney filtration barrier are a leading cause of ESRD. Most disorders affect the podocytes, polarized cells with a limited capacity for self-renewal that require tightly controlled signaling to maintain their integrity, viability, and function. Here, we provide an atlas of in vivo phosphorylated, glomerulus-expressed proteins, including podocyte-specific gene products, identified in an unbiased...
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