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Article

Molecular mechanisms of varicella zoster virus pathogenesis.

Nature reviews. Microbiology - 1 Mar 2014

Zerboni Leigh, Sen Nandini, Oliver Stefan L, Arvin Ann M

Abstract excerpt

Varicella zoster virus (VZV) is the causative agent of varicella (chickenpox) and zoster (shingles). Investigating VZV pathogenesis is challenging as VZV is a human-specific virus and infection does not occur, or is highly restricted, in other species. However, the use of human tissue xenografts in mice with severe combined immunodeficiency (SCID) enables the analysis of VZV infection in differentiated human...

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Identifiers

PMID: 24509782
DOI: 10.1038/nrmicro3215
PMCID: PMC4066823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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