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Article

Characterization of Langerin-Expressing Dendritic Cell Subsets in the Normal Cornea

12 Apr 2011

Abstract excerpt

PURPOSE: In addition to Langerhans cells (LCs), other dendritic cells (CD11c(+)) have recently been shown to express Langerin (c-type lectin). In skin, (non-LC) Langerin+ dendritic cells initiate adaptive immunity. However, whether such dendritic cells (DC) reside in the cornea, an immune-privileged tissue, is unknown. METHODS: Normal C57BL/6 corneas were harvested for qRT-PCR analyses of Langerin expression in...

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PMID: 21482644
DOI: 10.1167/iovs.10-6741

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