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Article

Positive clinical response to clopidogrel is independent of paraoxonase 1 Q192R and CYP2C19 genetic variants.

Journal of clinical pharmacology - 1 Aug 2014

Martínez-Quintana Efrén, Medina-Gil José M, Rodríguez-González Fayna, Garay-Sánchez Paloma, Limiñana José M, Saavedra Pedro, Tugores Antonio

Abstract excerpt

There is increasing controversy about the influence of serum paraoxonase type 1 and cytochrome CYP2C19 in the conversion of clopidogrel to its pharmaceutically active metabolite. The effect of concomitant medication with the proton pump inhibitor omeprazole has been also subject of intense scruti...

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Source

Identifiers

PMID: 24504666
DOI: 10.1002/jcph.275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24504666-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Positive clinical response to clopidogrel is independent of paraoxonase 1 Q192R and CYP2C19 genetic variants.PMID 24504666Read ↗

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