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Article

Next generation sequencing improves the accuracy of KRAS mutation analysis in endoscopic ultrasound fine needle aspiration pancreatic lesions.

PloS one - 1 Jan 2014

de Biase Dario, Visani Michela, Baccarini Paola, Polifemo Anna Maria, Maimone Antonella, Fornelli Adele, Giuliani Adriana, Zanini Nicola, Fabbri Carlo, Pession Annalisa, Tallini Giovanni

Abstract excerpt

The use of endoscopic ultrasonography has allowed for improved detection and pathologic analysis of fine needle aspirate material for pancreatic lesion diagnosis. The molecular analysis of KRAS has further improved the clinical sensitivity of preoperative analysis. For this reason, the use of highly analytical sensitive and specific molecular tests in the analysis of material from fine needle aspirate specimens...

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Topics

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Share to Carcinoma, Pancreatic Ductal
Share to Endoscopic Ultrasound-Guided Fine Needle Aspiration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 24504548
DOI: 10.1371/journal.pone.0087651
PMCID: PMC3913642

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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