Article
Unraveling the hidden heterogeneities of breast cancer based on functional miRNA cluster.
PloS one - 1 Jan 2014
Li Li, Liu Chang, Wang Fang, Miao Wei, Zhang Jie, Kang Zhiqian, Chen Yihan, Peng Luying
Abstract excerpt
It has become increasingly clear that the current taxonomy of clinical phenotypes is mixed with molecular heterogeneity, which potentially affects the treatment effect for involved patients. Defining the hidden molecular-distinct diseases using modern large-scale genomic approaches is therefore useful for refining clinical practice and improving intervention strategies. Given that microRNA expression profiling...
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