Article
Cell surface area and membrane folding in glioblastoma cell lines differing in PTEN and p53 status.
PloS one - 1 Jan 2014
Memmel Simon, Sukhorukov Vladimir L, Höring Marcus, Westerling Katherine, Fiedler Vanessa, Katzer Astrid, Krohne Georg, Flentje Michael, Djuzenova Cholpon S
Abstract excerpt
Glioblastoma multiforme (GBM) is characterized by rapid growth, invasion and resistance to chemo-/radiotherapy. The complex cell surface morphology with abundant membrane folds, microvilli, filopodia and other membrane extensions is believed to contribute to the highly invasive behavior and thera...
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