Article
Novel phage display-derived H5N1-specific scFvs with potential use in rapid avian flu diagnosis.
Journal of microbiology and biotechnology - 1 May 2014
Wu Jie, Zeng Xian-Qiao, Zhang Hong-Bin, Ni Han-Zhong, Pei Lei, Zou Li-Rong, Liang Li-Jun, Zhang Xin, Lin Jin-Yan, Ke Chang-Wen
Abstract excerpt
The highly pathogenic avian influenza A (HPAI) viruses of the H5N1 subtype infect poultry and have also been spreading to humans. Although new antiviral drugs and vaccinations can be effective, rapid detection would be more efficient to control the outbreak of infections. In this study, a phage-display library was applied to select antibody fragments for HPAI strain A/Hubei/1/2010. As a result, three clones were...
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