Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishing a diagnostic road map for MUTYH-associated polyposis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2014

Borras Ester, Taggart Melissa W, Lynch Patrick M, Vilar Eduardo

Abstract excerpt

The analysis of MUTYH-associated polyposis cases of the EPIPOLIP cohort confirms the importance of including serrated polyps in the diagnostic work-up of patients with oligopolyposis, suggests a role for screening polyps for the somatic c.34G>T KRAS mutation, and allows the implementation of a genetic testing strategy based on population data.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Colonic Polyps
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Glycosylases

Share to KRAS gene

Share to MUTYH gene

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 24486588
DOI: 10.1158/1078-0432.CCR-13-3295
PMCID: PMC3996649

Genes

MUTYH
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishing a diagnostic road map for MUTYH-associated polyposis.PMID 24486588Read ↗

MutYH-associated polyposisSemantic proximity Read ↗

[MUTYH-associated polyposis: Review and update of the French recommendations established in 2012 under the auspices of the National Cancer Institute (INCa)].Semantic proximity Read ↗

Hereditary Colorectal Tumors: A Literature Review on MUTYH-Associated PolyposisSemantic proximity Read ↗

The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk managementSemantic proximity Read ↗

Filling the gap: A thorough investigation for the genetic diagnosis of unsolved polyposis patients with monoallelic MUTYH pathogenic variants.Semantic proximity Read ↗

Hamartomatous polyps: Diagnosis, surveillance, and managementSemantic proximity Read ↗

Unexplained polyposis: a challenge for geneticists, pathologists and gastroenterologistsSemantic proximity Read ↗

Prevalence and characteristics of MUTYH-associated polyposis in patients with multiple adenomatous and serrated polyps.Semantic proximity Read ↗

MUTYH-Associated Polyposis: The Irish Experience>.Semantic proximity Read ↗

Presentation and Follow-up of Familial Adenomatous Polyposis: Differences Between APC and MUTYH Mutations.Semantic proximity Read ↗

Germline variant testing in serrated polyposis syndromeSemantic proximity Read ↗

Familial adenomatous polyposis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.