Article
Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis.
Genes, chromosomes & cancer - 1 May 2014
Ruland Vincent, Hartung Stefan, Kordes Uwe, Wolff Johannes E, Paulus Werner, Hasselblatt Martin
Abstract excerpt
Choroid plexus carcinoma is a malignant brain tumor predominantly occurring in young children. Only limited data are available regarding the underlying molecular genetic alterations. Therefore, molecular inversion probe single nucleotide polymorphism (MIP SNP) arrays were performed on a series of 26 neuropathologically well-characterized choroid plexus carcinomas. Recurrent copy number losses of chromosomes 5, 6,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
