Article
Increased oxidative stress tolerance results in general stress tolerance in Candida albicans independently of stress-elicited morphological transitions.
Folia microbiologica - 1 Jul 2014
Jakab Ágnes, Antal Károly, Kiss Ágnes, Emri Tamás, Pócsi István
Abstract excerpt
A selection of tert-butylhydroperoxide (tBOOH)-tolerant Candida albicans mutants showed increased tolerances to 19 different stress conditions. These mutants are characterized by a constitutively upregulated antioxidative defense system and, therefore, adaptation to oxidative stress may play an important role in gaining general stress tolerance in C. albicans. Although C. albicans cells may undergo morphological...
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