Article
Clinical utility of chromogranin A in SDHx-related paragangliomas.
European journal of clinical investigation - 1 Apr 2014
Zuber Samuel, Wesley Robert, Prodanov Tamara, Eisenhofer Graeme, Pacak Karel, Kantorovich Vitaly
Abstract excerpt
BACKGROUND: Measurement of plasma/urinary catecholamine metabolites--especially normetanephrine (NMN)--represents a gold standard in biochemical detection of succinate dehydrogenase subunit B (SDHB) and D (SDHD)-related pheochromocytomas (PHEO) and paragangliomas (PGL). This study was designed to assess diagnostic utility of chromogranin A (CgA) alone or in combination with NMN in patients with PHEO/PGL related...
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