Article
Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis.
Trends in microbiology - 1 Sept 1995
Deretic V, Schurr M J, Yu H
Abstract excerpt
During chronic infections in cystic fibrosis, persistence of Pseudomonas aeruginosa is associated with conversion into forms that are associated with conversion into forms that are characterized by a mucoid colony morphology, rough lipopolysaccharide and, paradoxically, decreased systemic virulence. The mutations underlying these changes occur in global regulators, such as alternative sigma factors and their...
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