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Next-Generation Sequencing of Cancer Genomes: Back to the Future

1 Nov 2009

Abstract excerpt

The systematic karyotyping of bone marrow cells was the first genomic approach used to personalize therapy for patients with leukemia. The paradigm established by cytogenetic studies in leukemia (from gene discovery to therapeutic intervention) now has the potential to be rapidly extended with the use of whole-genome sequencing approaches for cancer, which are now possible. We are now entering a period of...

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PMID: 20161678
DOI: 10.2217/pme.09.52

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