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Article

Next-generation sequencing for MRD monitoring in B-lineage malignancies: from bench to bedside

3 Sept 2022

Abstract excerpt

Minimal residual disease (MRD) is considered the strongest relevant predictor of prognosis and an effective decision-making factor during the treatment of hematological malignancies. Remarkable breakthroughs brought about by new strategies, such as epigenetic therapy and chimeric antigen receptor-T (CAR-T) therapy, have led to considerably deeper responses in patients than ever, which presents difficulties with...

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PMID: 36057673
DOI: 10.1186/s40164-022-00300-2

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