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Next-generation sequencing applied to molecular diagnostics

1 May 2011

Abstract excerpt

Next-generation sequencing technologies have begun to revolutionize the field of cancer genetics through rapid and accurate assessment of a patient's DNA makeup with minimal cost. These technologies have already led to the realization of the inter- and intra-tumor genetic heterogeneity and the identification of novel mutations and chimeric genes, however, several challenges lie ahead. Given the low number of...

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PMID: 21545259
DOI: 10.1586/erm.11.18

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