Fructooligosacharides reduce Pseudomonas aeruginosa PAO1 pathogenicity through distinct mechanisms.

doi:10.1371/journal.pone.0085772

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Article

Fructooligosacharides reduce Pseudomonas aeruginosa PAO1 pathogenicity through distinct mechanisms.

PloS one - 1 Jan 2014

Ortega-González Mercedes, Sánchez de Medina Fermín, Molina-Santiago Carlos, López-Posadas Rocío, Pacheco Daniel, Krell Tino, Martínez-Augustin Olga, Abdelali Daddaoua

Abstract excerpt

Pseudomonas aeruginosa is ubiquitously present in the environment and acts as an opportunistic pathogen on humans, animals and plants. We report here the effects of the prebiotic polysaccharide inulin and its hydrolysed form FOS on this bacterium. FOS was found to inhibit bacterial growth of strain PAO1, while inulin did not affect growth rate or yield in a significant manner. Inulin stimulated biofilm formation,...

Topics

ADP Ribose Transferases
Animals
Bacterial Proteins
Bacterial Toxins
Biofilms
Blotting, Western
Cell Line
Cells, Cultured
Cytokines
DNA-Binding Proteins
Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Exotoxins

Female

Insulin

Interleukin-10

Interleukin-6

Macrophages

Mutation

Source

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PMID: 24465697
DOI: 10.1371/journal.pone.0085772
PMCID: PMC3899050

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