Article
The role of NQO1 polymorphisms in the susceptibility and chemotherapy response of Chinese NSCLC patients.
Cell biochemistry and biophysics - 1 Jul 2014
Tian Gang, Wang Miaomiao, Xu Xiaogang
Abstract excerpt
To investigate whether the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene polymorphisms determine the Platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC) in a Chinese cohort. A total of 391 patients with inoperable advanced stage of NSCLC, namely, stage III (A + B) and IV NSCLC, and 663 age-and sex-matched healthy were enrolled. The effects of chemotherapy were evaluated. NQO1 C609T...
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