The role of NQO1 polymorphisms in the susceptibility and chemotherapy response of Chinese NSCLC patients.

doi:10.1007/s12013-014-9820-z

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Article

The role of NQO1 polymorphisms in the susceptibility and chemotherapy response of Chinese NSCLC patients.

Cell biochemistry and biophysics - 1 Jul 2014

Tian Gang, Wang Miaomiao, Xu Xiaogang

Abstract excerpt

To investigate whether the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene polymorphisms determine the Platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC) in a Chinese cohort. A total of 391 patients with inoperable advanced stage of NSCLC, namely, stage III (A + B) and IV NS...

Topics

Aged
Asian People
Carcinoma, Non-Small-Cell Lung
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Male
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Single Nucleotide
Treatment Outcome

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