Article
Association of obesity with proteasomal gene polymorphisms in children.
Journal of obesity - 1 Jan 2013
Kupca Sarmite, Sjakste Tatjana, Paramonova Natalija, Sugoka Olga, Rinkuza Irena, Trapina Ilva, Daugule Ilva, Sipols Alfred J, Rumba-Rozenfelde Ingrida
Abstract excerpt
The aim of this study was to ascertain possible associations between childhood obesity, its anthropometric and clinical parameters, and three loci of proteasomal genes rs2277460 (PSMA6 c.-110C>A), rs1048990 (PSMA6 c.-8C>G), and rs2348071 (PSMA3 c. 543+138G>A) implicated in obesity-related diseases. Obese subjects included 94 otherwise healthy children in Latvia. Loci were genotyped and then analyzed using...
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