Article
Procolipase gene: no association with early-onset obesity or fat intake.
Obesity facts - 1 Jan 2009
Wermter Anne-Kathrin, Scherag André, Holter Katja, Reichwald Kathrin, Lichtner Peter, Siegfried Wolfgang, Blundell John, Lawton Clare, Whybrow Stephen, Stubbs James, Arch Jonathan R, Meitinger Thomas, Platzer Matthias, Hinney Anke, Hebebrand Johannes
Abstract excerpt
BACKGROUND: Several lines of evidence in volvement of procolipase (CLPS) or its derivative enterostatin in dietary fat absorption, regulation of fat intake, and body weight in rodents. We explored the relationship between genetic variation in CLPS, early-onset obesity and fat intake in humans. METHODS: We screened the CLPS in 93 extremely obese children and adolescents and 96 underweight young adults for sequence...
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