Article
A two-stage association study suggests BRAP as a susceptibility gene for schizophrenia.
PloS one - 1 Jan 2014
Zhang Fuquan, Liu Chenxing, Xu Yong, Qi Guoyang, Yuan Guozhen, Cheng Zaohuo, Wang Jidong, Wang Guoqiang, Wang Zhiqiang, Zhu Wei, Zhou Zhenhe, Zhao Xingfu, Tian Lin, Jin Chunhui, Yuan Janmin, Zhang Guofu, Chen Yaguang, Wang Lifang, Lu Tianlan, Yan Hao, Ruan Yanyan, Yue Weihua, Zhang Dai
Abstract excerpt
Schizophrenia (SZ) is a neurodevelopmental disorder in which altered immune function typically plays an important role in mediating the effect of environmental insults and regulation of inflammation. The breast cancer suppressor protein associated protein (BRAP) is suggested to exert vital effects in neurodevelopment by modulating the mitogen-activated protein kinase cascade and inflammation signaling. To explore...
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