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Article

Single Cell Stochastic Regulation of Pilus Phase Variation by an Attenuation-like Mechanism

16 Jan 2014

Abstract excerpt

The molecular triggers leading to virulence of a number of human-adapted commensal bacteria such as Streptococcus gallolyticus are largely unknown. This opportunistic pathogen is responsible for endocarditis in the elderly and associated with colorectal cancer. Colonization of damaged host tissues with exposed collagen, such as cardiac valves and pre-cancerous polyps, is mediated by appendages referred to as Pil1...

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PMID: 24453966
DOI: 10.1371/journal.ppat.1003860

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