Article
Pharmacogenetics at 50: genomic personalization comes of age.
Science translational medicine - 22 Jan 2014
Urban Thomas J, Goldstein David B
Abstract excerpt
The study of the genetics of drug responses has a long history but has provided only a few examples of gene variants that are relevant clinically. Here, we discuss the current state of the pharmacogenomics field with emphasis on the potential of data generated through drug development in order to shed new light on genetic variants predictive of therapeutic outcomes-and likewise the potential of pharmacogenomics...
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