Article
[The effectiveness of fractionated exposure of sarcoma M-1 to gamma-radiation and fast neutrons].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Iuzhakov V V, Sevan'kaeva L E, Ul'ianenko S E, Iakovleva N D, Kuznetsova M N, Tsyganova M G, Fomina N K, Ingel' I E, Lychagin A A
Abstract excerpt
The effectiveness of fractionated exposure to gamma- and neutron radiation in their separate and combined use on the growth and functional morphology of mutant p53 sarcoma M-1 in rats was studied. Investigation techniques included immunostaining of PCNA and mutant p53 expressing cells, determination of mitotic activity and apoptotic death of tumor cells, as well as computer analysis of microscopic images. The...
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