Article
Single nucleotide polymorphisms in the cadherin 23 (CDH23) gene in Polish workers exposed to industrial noise.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Sliwinska-Kowalska Mariola, Noben-Trauth Konrad, Pawelczyk Malgorzata, Kowalski Tomasz Jarema
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most frequent type of variation in the human genome and may underlie differential susceptibility to common genetic diseases. A candidate gene for susceptibility to noise-induced hearing loss (NIHL) is Cadherin 23 (CDH23). This study aimed to analyze genetic variation in the CDH23 gene in a group of 10 individuals derived from a cohort of 949 workers exposed to noise,...
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