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Article

Effect of the -148C/T, 448G/A, and -854G/A Polymorphisms of the β-Fibrinogen Gene on the Risk of Ischemic Stroke in Chinese Population.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jul 2015

Wu Guangliang, Cai Haiyan, Cai Haobin, Chen Zhao, Tan Lei, Qi Huitao, Cai Yefeng

Abstract excerpt

BACKGROUND: Several investigations have been performed to examine the influence of the β-fibrinogen (FGβ) gene polymorphisms on the risk of ischemic stroke, but the results of these studies are controversial. Our study aimed at investigating whether the FGβ gene (-148 C/T, 448 G/A, and -854 G/A) polymorphisms were associated with susceptibility to ischemic stroke by conducting meta-analysis. METHODS: Relevant...

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PMID: 25890854
DOI: 10.1016/j.jstrokecerebrovasdis.2015.03.029

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