Article
The prevalence of 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene in central serous chorioretinopathy and its association with plasma PAI-1 levels.
Cutaneous and ocular toxicology - 1 Dec 2014
Sogutlu Sari Esin, Yazici Alper, Eser Betül, Erol Muhammet Kazim, Kilic Adil, Ermis Sitki Samet, Koytak Arif, Akşit Hasan, Yakut Tahsin
Abstract excerpt
CONTEXT: Central serous chorioretinopathy (CSCR) is a poorly understood disease and the choroidal circulation abnormality induced by the plasminogen activator inhibitor type 1 (PAI-1) seems to be associated with the pathogenesis. There are many reports indicating that 4 G/5 G polymorphism of the PAI-1 gene is a risk factor for several diseases related to the elevated serum levels of PAI-1. OBJECTIVE: To evaluate...
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