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Article

Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts

18 Jan 2014

Abstract excerpt

MicroRNAs are small noncoding RNAs that inhibit protein expression. We have previously shown that the inhibition of the microRNA let-7d in epithelial cells caused changes consistent with epithelial-to-mesenchymal transition (EMT) both in vitro and in vivo. The aim of this study was to determine whether the introduction of let-7d into fibroblasts alters their mesenchymal properties. Transfection of primary...

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PMID: 24441869
DOI: 10.1152/ajplung.00149.2013

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